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What is Semaglutide?
Semaglutide is a medication that has gained attention for its effectiveness in weight loss management. Originally developed for the treatment of type 2 diabetes, it has shown significant promise in aiding weight loss, leading to its approval for this purpose under the brand names Wegovy and Ozempic.
How Semaglutide Works
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. It mimics the GLP-1
hormone, which helps to regulate appetite and food intake. By binding to GLP-1 receptors in the brain, it can reduce hunger, increase feelings of fullness, and slow gastric emptying, which collectively contribute to reduced calorie intake and weight loss.
Efficacy
Clinical trials have demonstrated substantial weight loss in participants using Semaglutide. In a key trial, individuals taking a 2.4 mg dose of semaglutide lost, on average, around 15% of their body weight over 68 weeks compared to those taking a placebo.
Dosage and Administration
Semaglutide for weight loss is typically as a subcutaneous injection once weekly. The dose is gradually increased over several weeks to minimize gastrointestinal side effects. Starting with a lower dose and gradually increasing helps the body adjust to the medication.
Side Effects
Common side effects include nausea, vomiting, diarrhea, constipation, and abdominal pain. These side effects are usually mild to moderate and tend to decrease over time. However, some individuals may experience more severe gastrointestinal issues.
Considerations and Contraindications
Semaglutide is not suitable for everyone. It should not be used by individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. Additionally, it should be used cautiously in individuals with a history of pancreatitis.
Integration with Lifestyle Changes
For optimal results, semaglutide should be used in conjunction with a reduced-calorie diet and increased physical activity. Behavioral changes and support are critical components of a successful weight management program alongside medication.
Conclusion
Semaglutide represents a significant advancement in the medical management of obesity. Its ability to induce substantial weight loss offers hope to many individuals struggling with weight management. However, it is important to use it under medical supervision, considering the potential side effects and contraindications.
If you’re ready to explore the benefits of Semaglutide yourself, Nurse Patricia Allen at Sacred Healing Wellness Center is here to help. Book your weight loss consultation appointment now by visiting
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678.665.2046
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References
Wilding, J. P. H., et al. (2021). “Once-Weekly Semaglutide in Adults with Overweight or Obesity.” New England Journal of Medicine, 384(11), 989-1002.
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